In vitro maturation (IVM)
IVM collects eggs before they're fully mature and matures them in the lab, with little or no stimulation. Who may benefit and how it works.
On this page
In vitro maturation (IVM) is a form of IVF that uses little or no stimulating medication. Instead of maturing inside the ovary, the eggs finish maturing in our laboratory.
How IVM works
- Eggs are collected a few days after your period starts, either without stimulation or after about 3 days of minimal stimulation.
- The eggs mature in the lab for 1 to 2 days in a special culture medium.
- Once mature, the eggs are either frozen for later use or fertilized with sperm using ICSI.
- The lining of the uterus is prepared, and embryos are transferred into the uterus.
Who should consider IVM
IVM may be an option for:
- Young women with polycystic ovary syndrome (PCOS)
- Women with a history of severe ovarian hyperstimulation syndrome (OHSS)
- Women whose previous IVF cycles were unsuccessful because of poor egg quality
- Women with an estrogen-sensitive cancer, such as breast cancer, who want to preserve their fertility
- Some women with premature ovarian dysfunction
For select women, IVM cycles may lead to pregnancy rates comparable to conventional IVF. Dr. Elassar will talk with you about whether it fits your situation. You can also read about preserving fertility before medical treatment.
This article is general information, not medical advice. Every situation is different, so talk with your doctor about yours.
